Pregnancy-induced cholestasis (more commonly called intrahepatic cholestasis of pregnancy, ICP) is a liver condition that happens during pregnancy, usually in the third trimester. It can sound scary, so here’s a clear, no-fluff breakdown. What it is ICP happens when pregnancy hormones slow the normal flow of bile from the liver. Bile acids then build up in the blood instead of flowing into the digestive system. Main symptom Intense itching (often the first and biggest sign) Typically no rash Worse at night Commonly affects palms of the hands and soles of the feet, but can be all over Other possible symptoms Dark urine Pale stools Fatigue Mild jaundice (yellowing of skin/eyes – less common) Why it matters For the mother: uncomfortable but usually resolves after delivery For the baby: increased risk of complications, especially if bile acids are high (preterm birth, fetal distress), which is why close monitoring is important How it’s diagnosed Blood tests, mainly: Elevated serum bile acids Abnormal liver function tests (ALT, AST) Treatment & management Ursodeoxycholic acid (UDCA) – helps reduce bile acids and itching Regular blood tests Close fetal monitoring Doctors often recommend early delivery (commonly around 37–38 weeks, depending on bile acid levels) After delivery Symptoms usually disappear within days to weeks Liver tests return to normal Important to recheck labs postpartum Higher chance of recurrence in future pregnancies If you’re asking because you or someone close to you has symptoms, don’t ignore itching—especially without a rash. It’s absolutely worth getting checked.